Nontraumatic Cervicothoracic Syrinx as a Cause of Progressive Neurologic Dysfunction

An Insidious Cardiac Sarcoma Presenting with Progressive Neurologic Dysfunction

Central nervous system metastases as the presentation of primary cardiac sarcoma are a very rare entity, with only a few previously reported cases. Sarcomas specifically make up 10 to 20% of all primary cardiac tumors. Patients with primary cardiac tumors typically present with cardiac symptomatology that may include arrhythmias, obstruction to blood flow and valve function, or symptoms of hear...

Zika Virus as a Cause of Neurologic Disorders.

Z virus infections have been known in Africa and Asia since the 1940s, but the virus’s geographic range has expanded dramatically since 2007. Between January 1, 2007, and March 1, 2016, local transmission was reported in an additional 52 countries and territories, mainly in the Americas and the western Pacific, but also in Africa and southeast Asia. Zika virus infections acquired by travelers v...

Mitochondrial dysfunction as a cause of ageing.

Mitochondrial dysfunction is heavily implicated in the ageing process. Increasing age in mammals correlates with accumulation of somatic mitochondrial DNA (mtDNA) mutations and decline in respiratory chain function. The age-associated respiratory chain deficiency is typically unevenly distributed and affects only a subset of cells in various human tissues, such as heart, skeletal muscle, coloni...

Cervical syrinx as a cause of shoulder pain in 2 athletes.

Spontaneous resolution of an extensive posttraumatic syrinx.

The prevalence of symptomatic syringomyelia in patients with chronic spinal cord injury (SCI) is around 4.5%. It is an important cause of treatable neurologic deterioration, although surgical shunting of the syrinx or arachnoid adhesiolysis of tethered elements have unpredictable results. Classically, syrinx extension causes progressive neuropathic pain, often with dissociated sensory loss due ...